Cri-du-chat syndrome is caused by a deletion of the end of the short (p) arm of chromosome 5. This chromosomal change is written as 5p-. This chromosomal change is written as 5p-. The size of the deletion varies among affected individuals; studies suggest that larger deletions tend to result in more severe intellectual disability and developmental delay than smaller deletions. 85 rows · Nov 02, · Cri du chat syndrome is due to a missing piece (deletion) of a specific part of chromosome 5 known as the 'p' arm. In general, the severity of the symptoms is determined by the size and location of the deletion on chromosome 5. This deletion occurs very early in the development of an embryo and cri du chat syndrome is usually not inherited in families.
Jun 29, · Cri du chat syndrome - also known as 5p- syndrome and cat cry syndrome - is a rare genetic condition that is caused by the deletion (a missing piece) of genetic material on the small arm (the p arm) of chromosome 5. The cause of this rare chromosomal deletion is unknown. What are the symptoms of cri du chat syndrome? However, most individuals with Cri-du-chat syndrome live into adulthood. There are adults with Cri-du-chat syndrome in the medical literature who have been reported to live over the age of fifty. With better treatments available to treat some of the symptoms of Cri-du-chat syndrome, the life expectancy for individuals with Cri-du-chat syndrome may further improve.